2-氯-5-硝基-N-苯基苯酰胺
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产品名称:2-氯-5-硝基-N-苯基苯酰胺CAS:22978-25-2别名：2-氯-5-硝基-N-苯基苯酰胺;2-氯-5-硝基苯甲酰苯胺英文名：GW9662
- 熔点 171-175 °C(lit.)
- 储存条件 2-8°C
- 溶解度 DMSO: 26 mg/mL, soluble
- 形态solid
- 颜色white
- CAS 数据库22978-25-2(CAS DataBase Reference)
- 用途 A cell-permeable, selective and irreversible PPARγ antagonist (IC50 = 3.3 nM, 32 nM, and 2 碌M for PPARγ, PPARα, and PPARδ, respectively). Reported to covalently modify a cysteine residue in the binding site of PPAR. At a concentration of 10 碌M, also acts as an agonist of human pregnane X receptor (PXR) and farnesoid X receptor (FXR). Does not activate liver X receptor-a (LXRa), retinoic acid receptor (RAR), retinoid X receptor-a (RXRa) and thyroid receptors a and b (TRa and TRb
