Bikinin
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产品名称:BikininCAS:188011-69-0别名：4-[(5-溴吡啶-2-基)氨基]-4-氧代丁酸英文名：Bikinin
- 熔点 144°C(lit.)
- 密度 1.711
- 储存条件 2-8°C
- 溶解度 DMSO: ≥5mg/mL
- 颜色white to tan
- InChIKeyXFYYQDHEDOXWGA-UHFFFAOYSA-N
- 生物活性Bikinin是一种ATP竞争性Arabidopsis GSK-3抑制剂，作为油菜素类固醇(BR)信号的一种强效活化剂发挥作用。
- 体外研究Bikinin directly targets BIN2 of Arabidopsis GSK-3s and activates brassinosteroid-dependent gene expression. Bikinin also inhibits RD26 expression, and inhibits the induction of GUS activity by 150 mM NaCl in the RD26pro:GUS line.
- 体内研究Bikinin strongly inhibits abscisic acid signaling outputs, and inhibits T180 phosphorylation of SnRK2.3 and its kinase activity in vivo.
